The project has unique and innovative impacts for both spaceflight and Earth (e.g., the public) through the evaluation of the SmartSleep headband technology, which is a new, non-invasive, brain stimulation technology to promote sleep depth and quality. This project proposes to evaluate this technology in a controlled, double-blind, laboratory study of non-invasive brain stimulation in healthy normal astronaut-like adults, to evaluate whether slow wave sleep enhancement via the SmartSleep stimulus algorithms could benefit cognitive performance during sleep restriction, and/or decrease the severity and duration of sleep inertia after abrupt awakening from sleep. SmartSleep consists of a headband worn during sleep and a sleep app. This approach to improving sleep quality and the cognitive benefits of sleep is now available as "SmartSleep," a new technology that enhances slow waves using inaudible acoustic stimulation during sleep. Studies have found that unconscious sound enhancement of electroencephalogram (EEG) slow waves during sleep can increase subsequent cognitive performance. Thus, there is a need for a technology that can improve sleep quality in space and biologically maximize the performance benefits of limited sleep duration, without unduly affecting the ability of astronauts to awaken abruptly due to an inflight emergency. Sleep medications have been used in spaceflight to promote better sleep quality and longer sleep duration sleep, but these have also been shown to markedly compromise the cognitive performance capability of astronauts when an emergency awakening requires them to function effectively. Sleep in spaceflight is often reduced in duration and of reduced quality, which Earth-based studies show can reduce waking cognitive performance. NOTE: End date changed to per TRISH (Ed., 1/8/21) Solicitation / Funding Source: 2018 TRA BRASH1801: Translational Research Institute for Space Health (TRISH) Biomedical Research Advances for Space Health Grant/Contract No.: NNX16AO69A-T0408 Project Type: GROUND Flight Program: TechPort: Yes Responsible Center: TRISH Grant Monitor: Center Contact: Unique ID: 12180
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